Tourniquet-induced ischemia-reperfusion injuries during extremity surgery at children's age: impact of anesthetic chemical structure
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چکیده
منابع مشابه
Administration of FTY720 during Tourniquet-Induced Limb Ischemia Reperfusion Injury Attenuates Systemic Inflammation
Acute ischemia-reperfusion injury (IRI) of the extremities leads to local and systemic inflammatory changes which can hinder limb function and can be life threatening. This study examined whether the administration of the T-cell sequestration agent, FTY720, following hind limb tourniquet-induced skeletal muscle IRI in a rat model would attenuate systemic inflammation and multiple end organ inju...
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In this study, we hypothesized that non-invasive continuous wave near-infrared spectroscopy (CWNIRS) can determine the severity or reversibility of muscle damage due to ischemia/reperfusion (I/R), and the results will be highly correlated with those from physical examination and histological analysis. To test this hypothesis, we performed CWNIRS measurements on two groups of male Sprague-Dawley...
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Objective(s): Crocus sativus (saffron) has been widely used in traditional medicine. It has also been found to possess many beneficial properties in modern medicine. The most important ingredients of saffron are crocin, crocetin, safranal, and picrocrocin. This study evaluated the protective effects of crocin against the inflammation, oxidative stress, and functional disturbances of the kidney ...
متن کاملبررسی اثرات همودینامیک و تنفسی آماد هسازی ایسکمیک دور در بیماران تحت جراحی شکستگی اندام تحتانی
Aim and Background: Arterial tourniquets are used widely for extremity orthopedic surgeries with regional or general anesthesia to reduce blood loss, but the harmful effect of ischemia and reperfusion is not clear yet. Materials and Methods: In this clinical trial 40 patients scheduled for lower extremity surgery with pneumatic tourniquet were randomized into 2 groups: a remote ischemi...
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ژورنال
عنوان ژورنال: Redox Report
سال: 2013
ISSN: 1351-0002,1743-2928
DOI: 10.1179/1351000212y.0000000037